Health benefits of Forskolin supplements

Forskolin supplements are widely used to support fat burning and help in combating a variety of health issues. It has earned a reputation of being a fat burner and testosterone booster which makes it highly endearing to fitness freaks and athletes. There is a plethora of uses of which have been discussed here.

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What is Forskolin? 

Forskolin is an active component of the tuberous roots of Coleus, a member of the mint family that grows in the tropical and subtropical regions of Africa and Asia such as India, Nepal, Thailand and East African countries. The biological name of Coleus is Plectranthus barbatus. Forskolin, extracted from the roots of Coleus, has been used in many traditional medicine systems such as Ayurveda, the ancient Indian medicinal system. Forskolin increases the level of cellular messengers known as cAMP by activating the enzyme adenylyl cyclase which have led to it being used in experimental clinical researches.


One of the most popular uses of Forskolin is fat burning. A study conducted by the University of Kansas found that obese men who were given 250mg of 10 percent Forskolin- containing coleus twice a day reported a loss of 7.8 times more body fat, 34% more bio-available testosterone and a gain of 35% more bone mass than the obese men who were given a placebo. stimulates the release of stored fat from fat cells. Clinical experiments have shown that Forskolin may cause fat loss while preserving muscle mass. Even though, on the basis of experiments, it cannot be conclusively said that Forskolin can cause weight loss but it does protect against weight gain. A study conducted on obese women found that Forskolin reduces hunger and weight gain,

but does not reduce body fat in women. Therefore, Forskolin supplements can be used to reduce obesity by combining it with proper diet and exercise.

Forskolin has also been used to relieve bronchospasms during asthmatic attacks. This is attributed to its action of increasing the level of cAMP as described before which causes relaxation of the muscles around the bronchial tubes. Forskolin can also be used to treat hypertension. A study conducted in India found that Forskolin reduced blood pressure significantly in over 75% of the patients who participated in the test. Forskolin has been used intravenously to treat congestive heart failure and idiopathic congestive cardiomyopathy.

Forskolin can be used in the treatment of cancer by virtue of its ability to activate the enzyme protein phosphatase 2 that is responsible for rapid rate of cell division. A 2011 study by the University of Madrid found that the activation of phosphatase 2 enzyme by Forskolin had a detrimental effect on the rectal tumours. It has also been discovered that Forskolin causes apoptosis, a biological term for programmed cell death, in multiple myeloma cancer cells.

Forskolin can also be used to treat a host of other conditions such as erectile dysfunction, skin diseases, glaucoma, etc.

Side effects

The potential side effects are unclear yet it is believed that Forskolin supplements may negatively interact with calcium channel blockers, anti-platelet drugs, anti-hypertensive drugs and nitrates.


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